The LTC2495 is a 16-channel (eight differential), 16-bit, No LatencyDelta SigmaADC with Easy Drive technology and a 2-wire, I2C interface. The patented sampling scheme eliminates dynamic input current errors and the shortcomings of on-chip buffering through automatic cancellation of differential input current. This allows large external source impedances and rail-to-rail input signals to be directly digitized while maintaining exceptional DC accuracy. The LTC2495 includes programmable gain, a high accuracy temperature sensor, and an integrated oscillator. This device can be con? gured to measure an external signal (from combinations of 16 analog input channels operating in singleended or differential modes) or its internal temperature sensor. The integrated temperature sensor offers 1/2°C resolution and 2°C absolute accuracy. The LTC2495 can be con? gured to provide a programmable gain from 1 to 256 in 8 steps. The LTC2495 allows a wide common mode input range (0V to VCC), independent of the reference voltage. Any combination of single-ended or differential inputs can be selected and the ? rst conversion, after a new channel is selected, is valid. Access to the multiplexer output enables optional external ampli? ers to be shared between all analog inputs and auto calibration continuously removes their associated offset and drift.